Recently, articles about drinking and increasing the incidence of cancer have been on the top of the news, which has aroused heated discussion among netizens. Today, let’s talk about the risk of drinking and causing cancer? First of all, let’s understand how alcohol is metabolized in our body: ethanol (alcohol), acetaldehyde (the oxide of ethanol), acetic acid (the product of further oxidation of acetaldehyde, also known as vinegar)
The final metabolite is acetic acid, which is a kind of harmless substance. Like rice or glucose that we usually eat, it releases energy after recycling with tricarboxylic acid. After drinking, we will have fever, sweating and so on.
Does alcohol really increase the risk of cancer? It is not very critical whether the cancer can be transformed into acetic acid smoothly. In the whole metabolic process, aldehyde dehydrogenase (ALDH) plays a decisive role in the conversion of acetaldehyde into acetic acid. There are many aldehyde dehydrogenases in the human body. ALDH2, located in the mitochondria of cells, has the highest working efficiency. Its activity determines whether ethanol can be metabolized smoothly. When the working efficiency of ALDH2 decreases or it can not be decomposed at all, the accumulation of acetaldehyde in the body will increase the risk of cancer or disease. That’s why alcohol is a risk factor for cancer.
People who drink and blush notice that the working efficiency of ALDH2 in the body is reduced or the invalid protein has lost its activity. In medicine, ALDH2 * 2 mutants have been formed. People who drink and blush are particularly careful. They are born with genetic determination
So my friends, the final conclusion: special people should be careful to drink, allergic people should not drink, blushing people should be careful to drink. Friends also know what about drinking knowledge, welcome to comment below, thank you!